首页> 外文期刊>Pharmaceutical Chemistry Journal >ANTIOXIDANT ACTIVITY OF EXTRACTS FROM ALLIUM SCHOENOPRASUM L. AND RUBUS CHAMAEMORUS L. GROWING IN THE KOMI REPUBLIC
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ANTIOXIDANT ACTIVITY OF EXTRACTS FROM ALLIUM SCHOENOPRASUM L. AND RUBUS CHAMAEMORUS L. GROWING IN THE KOMI REPUBLIC

机译:在KOMI共和国生长的葱属和小菜蛾提取物的抗氧化剂活性

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摘要

New data for the antioxidant properties of the food plants Allium schoenoprasum and Rubus chamaemorus growing in the Komi Republic were obtained. The activity of the extracts on live bacteria under oxidative stress was studied. It was found that extracts of R. chamaemorus fruit and A. schoenoprasum bulbs had the greatest antioxidant effect and elevated antioxidant activity that was sufficient to protect the bacteria from peroxide stress. These extracts were shown to exhibit antioxidant activity on the bacteria simultaneously via several different pathways including direct inhibition of reactive oxygen species, chelation of iron ions, and induction of antioxidant genes. It was demonstrated for the first time that the ability of the extracts to activate OxyR-regulon genes and to affect the activity of the RpoS-controlled system of general oxidative stress response contributed significantly to the antioxidant activity of the studied extracts in bacteria cultures.
机译:获得了在科米共和国生长的食用植物葱兰和南美白菜的抗氧化特性的新数据。研究了提取物在氧化胁迫下对活细菌的活性。结果发现,R。chamaemorus水果和A. schoenoprasum鳞茎的提取物具有最大的抗氧化作用,并具有增强的抗氧化活性,足以保护细菌免受过氧化物胁迫。这些提取物显示出通过几种不同途径同时对细菌表现出抗氧化活性,包括直接抑制活性氧,螯合铁离子和诱导抗氧化基因。首次证明了提取物激活OxyR-regulon基因并影响RpoS调控的一般氧化应激反应系统活性的能力显着促进了所研究提取物在细菌培养物中的抗氧化活性。

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