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Phantom based point by point photon counting and imaging of human skin tissue

机译:基于幻影的人体皮肤组织逐点光子计数和成像

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Time-correlated single photon counting (TCSPC) is popular in the resolved techniques due to its prominent performance such as ultra-high time resolution and ultra-high sensitivity. This paper presents advance signal processing techniques on the optical TCSPC signals obtained from the series of experiments on fabricated tissue like phantom. A pulsed laser sources at a wavelength of 830 rim transmits the light through the surface of phantom and finally at receiver side, photon counting device generates the histogram of the receiving signal. The noisy data obtained from the photon counter is processed with the splitting based denoising method. The method divide the signal into different subsets based on the transitions. Each subset is then processed individually and final merging of all subsets gives noise free signal. The main objective of this work is to analyze the signal obtained from photon counter in context of skin blood absorption. We had examined the signal obtained by varying the distance between transmitter and receiver to extract the features. Experimental results with our prototype shows more scattering with the increase in the distance at 3dB level and hence less absorption with increase in the distance.
机译:时间相关的单光子计数(TCSPC)由于其卓越的性能(例如超高时间分辨率和超高灵敏度)而在解析技术中很受欢迎。本文介绍了对光学TCSPC信号的先进信号处理技术,该信号是通过对在组织(如体模)上进行的一系列实验获得的。波长为830 rim的脉冲激光源将光传输通过体模的表面,最后在接收器侧,光子计数设备将生成接收信号的直方图。从光子计数器获得的噪声数据将使用基于分裂的降噪方法进行处理。该方法基于转换将信号分为不同的子集。然后分别处理每个子集,并且所有子集的最终合并将给出无噪声信号。这项工作的主要目的是在皮肤吸收血液的情况下分析从光子计数器获得的信号。我们已经检查了通过改变发射器和接收器之间的距离以提取特征而获得的信号。我们的原型的实验结果表明,随着距离的增加,在3dB的水平上会有更多的散射,因此随着距离的增加,吸收会减少。

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