Synthesis and insecticidal evaluation of novel N-(S-amino)sulfenylated derivatives of diacylhydrazines

摘要

A series of new N-(S-amino)sulfenylated derivatives of diacylhydrazines were synthesized by the reaction of S-aminosulfenyl chlorides with N-tert-butyl-N'-benzoyl-N-substituted benzoylhydrazines in the presence of sodium hydride, and evaluated for moulting hormone mimicking activity. In the course of syntheses, N-N bond cleavage in diacylhydrazines was found and the reaction was studied in some detail. The results of bioassay showed that the title compounds exhibit excellent larvicidal activity. Toxicity assays indicated that these compounds can induce a premature, abnormal and lethal larval mount.