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Croup.

机译:臀部

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摘要

The management of mild to severe croup has undergone dramatic changes in the last 5 years, primarily due to the increased understanding of the benefits of treating it with steroids. Steroids have been used in the treatment of croup for many years, but, until recently, their use has remained controversial. Earlier studies were often not blinded or used inappropriate outcome measures, such as respiratory rate, which have not proven appropriate. Two attempts to review the literature in 1980 and 1989 cautiously supported the use of steroids. Despite these recommendations many practitioners continued to view croup in most cases as a benign self-limited condition, and since steroids have potential side-effects, their use was not considered justified. More recently, however, a number of developments such as the successful use of the inhaled steroid budesonide and oral dexamethasone have reinforced the argument for using steroids. Recent work has also shown that both inhaled and systemic steroids work by 1 hour and dramatically reduce morbidity and hospitalization time. The demonstration that an oral dose of 0.15 mg/kg dexamethasone is as effective as larger doses has made the use of systemic steroids more acceptable to many practitioners. All children with croup severe enough to be admitted to hospital should receive steroids. Two recent studies have shown that steroids also benefitted children who presented to emergency departments for treatment, but whose croup was not considered severe enough for admission. The type of steroid, the dose, and the mode of administration will need to be decided by the attending clinician.
机译:在过去的5年中,轻度到重度臀部的管理发生了巨大变化,这主要是由于人们越来越了解使用类固醇治疗其益处的认识。类固醇已被用于治疗臀部病多年,但直到最近,它们的使用仍存在争议。较早的研究通常没有盲目使用,也没有使用不合适的结局指标,例如呼吸频率,但事实证明这些指标不合适。在1980年和1989年进行的两次文献回顾尝试都谨慎地支持类固醇的使用。尽管有这些建议,但许多从业者在大多数情况下仍将臀部病视为良性的自限性疾病,并且由于类固醇具有潜在的副作用,因此认为使用类固醇是不合理的。然而,最近,许多进展,例如成功使用吸入的类固醇布地奈德和口服地塞米松,都增加了使用类固醇的争论。最近的研究还表明,吸入性和全身性类固醇均可在1小时内起作用,并大大减少了发病率和住院时间。 0.15 mg / kg地塞米松的口服剂量与大剂量一样有效的证明使全身性类固醇的使用更被许多医生所接受。所有臀部病严重到足以入院的儿童都应接受类固醇激素治疗。最近的两项研究表明,类固醇也有益于向急诊科就诊的儿童,但他们的臀部病并没有被认为严重到足以入院。类固醇的类型,剂量和给药方式将由主治医生决定。

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