Genome-Wide Analysis of DNA Copy Number Alterations and Loss of Heterozygosity in Intracranial Germ Cell Tumors

Terashima Keita; Yu Alexander; Chow Wing-Yuk T.; Hsu Wei-chun J.; Chen Peikai; Wong Stephen; Hung Yeung Sam; Suzuki Tomonari; Nishikawa Ryo; Matsutani Masao; Nakamura Hideo; Ng Ho-Keung; Allen Jeffrey C.; Aldape Kenneth D.; Su Jack M.; Adesina Adekunle M.; Leung Hon-chiu E.; Man Tsz-Kwong; Lau Ching C.

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Genome-Wide Analysis of DNA Copy Number Alterations and Loss of Heterozygosity in Intracranial Germ Cell Tumors

机译：颅内生殖细胞肿瘤中DNA拷贝数变化和杂合性缺失的全基因组分析

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BackgroundsIntracranial germ cell tumors (GCTs) are rare and heterogeneous with very little is known about their pathogenesis and underlying genetic abnormalities.

机译：背景颅内生殖细胞肿瘤（GCT）罕见且异质，对其发病机理和潜在的遗传异常知之甚少。

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《Pediatric blood & cancer》 |2014年第4期|共8页
作者
Terashima Keita; Yu Alexander; Chow Wing-Yuk T.; Hsu Wei-chun J.; Chen Peikai; Wong Stephen; Hung Yeung Sam; Suzuki Tomonari; Nishikawa Ryo; Matsutani Masao; Nakamura Hideo; Ng Ho-Keung; Allen Jeffrey C.; Aldape Kenneth D.; Su Jack M.; Adesina Adekunle M.; Leung Hon-chiu E.; Man Tsz-Kwong; Lau Ching C.;
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正文语种 eng
中图分类儿科学;
关键词
DNA copy number; genomic profiling; intracranial germ cell tumor; loss of heterozygosity; SNP microarray;

机译：DNA拷贝数;基因组图谱;颅内生殖细胞瘤;杂合性缺失;SNP芯片;

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专利

1. 鼻咽癌全基因组杂合性缺失分析 [J] . 邵建永, 王辉云, 黄晓明, 癌症（英文版） . 2001,第011期
2. Genome-Wide Analysis of DNA Copy Number Alterations and Loss of Heterozygosity in Intracranial Germ Cell Tumors [J] . Terashima Keita, Yu Alexander, Chow Wing-Yuk T., Pediatric blood & cancer . 2014,第4期

机译：颅内生殖细胞肿瘤中DNA拷贝数变化和杂合性缺失的全基因组分析
3. Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array [J] . Nan Hu, Chaoyu Wang, Ying Hu, BMC Genomics . 2006,第1期

机译：使用Affymetrix GeneChip Mapping 10 K阵列在食管鳞状细胞癌中全基因组范围内杂合性丧失和拷贝数改变
4. Genome-wide high-resolution analysis of DNA copy number alterations in NF1-associated malignant peripheral nerve sheath tumors using 32K BAC array. [J] . Mantripragada KK, de Stahl TD, Patridge C Genes, Chromosomes and Cancer . 2009,第10期

机译：全基因组高分辨率分析使用32K BAC阵列的与NF1相关的恶性周围神经鞘瘤中DNA拷贝数的变化。
5. Genome-wide DNA methylation analysis in tumor and normal tissues from lung squamous cell carcinoma and serous cystadenocarcinoma [C] . 2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops . 2010

机译：肺鳞状细胞癌和浆液性囊腺癌的肿瘤和正常组织中全基因组DNA甲基化分析
6. Primordial Germ Cell Differentiation in Vitro: A Model for Understanding Epigenetic Reprogramming and Genome-Wide DNA Demethylation in Mouse Primordial Germ Cells. [D] . Vincent, John James. 2013

机译：原始生殖细胞的体外分化：一种模型，用于了解小鼠原始生殖细胞中的表观遗传重编程和全基因组DNA去甲基化。
7. Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array [O] . Nan Hu, Chaoyu Wang, Ying Hu, 2006

机译：使用Affymetrix GeneChip Mapping 10 K阵列在食管鳞状细胞癌中全基因组范围内杂合性丧失和拷贝数改变
8. Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array [O] . 2006

机译：使用Affymetrix GeneChip Mapping 10 K阵列在食管鳞状细胞癌中全基因组范围内杂合性丧失和拷贝数改变

Genome-Wide Analysis of DNA Copy Number Alterations and Loss of Heterozygosity in Intracranial Germ Cell Tumors

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