Polysaccharide pneumococcal vaccination of nephrotic children at disease onset-long-term data.

摘要

Patients with nephrotic syndrome (NS) are at risk of developing pneumococcal infections, such as peritonitis, pneumonia+- pleural effusion, and meningitis [1], with the reported incidence of such infections population being 3-5% per year [1]. There is currently no consensus on how to prevent severe episodes of pneumococcal infections in NS children. Anti-pneumococcal vaccine is given to such patients in many centers, but the fear of relapse induced by the vaccine still causes many pediatricians to hesitate in prescribing this treatment.