首页> 外文期刊>Pediatric nephrology: journal of the International Pediatric Nephrology Association >Urinary diversion in children and adolescents with neurogenic bladder: the Mainz experience. Part II: Continent cutaneous diversion using the Mainz pouch I.
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Urinary diversion in children and adolescents with neurogenic bladder: the Mainz experience. Part II: Continent cutaneous diversion using the Mainz pouch I.

机译:儿童和青少年神经源性膀胱的尿流改道:美因茨的经验。第二部分:使用美因茨小袋进行大陆皮肤转移。

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摘要

After failure of conservative treatment of neurogenic bladders (deterioration of the upper urinary tract/incontinence) continent cutaneous diversion has to be considered in those patients with irreparable urethral sphincter defects or those who are unable to perform trans-urethral self-catheterization. In this second part of the study we investigated the long-term safety of using the Mainz pouch I with regard to protecting the upper urinary tracts and to provide urine continence. Between 1985 and 2002, operations to form an ileocaecal pouch with umbilical stoma (Mainz pouch I) were performed on 70 children and adolescents of median age 15.3 years (range 5.7-20 years). During the follow-up period five patients died 2.4-14 years postoperatively of causes not related to urinary diversion. A follow-up period of 8.7 years (0.9-18) was achieved in 65 patients with 118 renal units (RUs). As compared to preoperatively, the upper urinary tracts had remained stable or improved in 113/118 RUs (95.8%) at the latest follow-up. Complete continence was achieved in 97% of patients with a continent cutaneous diversion. Surgical revisions were required for: incontinence of the outlet mechanism in 9%, stoma prolapse in 2%, stoma stenosis in 23%, pouch calculi in 15%, symptomatic reflux in 1%, ureter stenosis in 16% of the RUs with submucosal tunnel and in 3% of the RUs with an extramural tunnel. We conclude that, in patients with irreparable sphincter defect and those who are unable to perform urethral self-catheterization, continent cutaneous urinary diversion with the Mainz pouch I provides a high continence rate with preservation of the upper urinary tracts in the long run. In patients with dilated ureters, the extramural tunnel technique results in a lower complication rate.
机译:在对神经源性膀胱进行保守治疗失败(上尿路/尿失禁恶化)失败之后,必须对那些具有不可修复的尿道括约肌缺陷的患者或无法进行经尿道自我导管插入术的患者考虑进行皮肤转移。在研究的第二部分中,我们研究了使用美因茨小袋I在保护上尿路和提供尿失禁方面的长期安全性。在1985年至2002年之间,对70名中位年龄为15.3岁(范围5.7-20岁)的儿童和青少年进行了手术,以形成带有脐部造口的回盲袋(Mainz袋I)。在随访期间,五名患者在术后2.4-14年死于与尿流改道无关的原因。 65名118个肾脏单位(RUs)的患者获得了8.7年(0.9-18)的随访期。与术前相比,在最近的随访中,上尿路保持稳定或改善了113/118 RU(95.8%)。 97%的大陆皮肤转移患者实现了完全节制。需要进行手术修订:粘膜下隧道的输尿管失禁9%,造口脱垂2%,造口狭窄23%,囊结石15%,症状性反流1%,输尿管狭窄16%。在3%的RU中设有壁外隧道。我们得出的结论是,对于患有无法修复的括约肌缺损的患者和无法进行尿道自我导尿的患者,使用美因茨小袋I进行大陆性皮肤尿路改道可提供较高的尿失禁率,并长期保留上尿路。在输尿管扩张的患者中,壁外隧道技术可降低并发症发生率。

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