A novel entry into a new class of (chromanone-pyrrolidine/pyrrolizidine/pyrrolo[1,2-c]thiazole/pyrrolo[1,2-a]isoquinoline)indane-1,3-dione ring systems through [3+2] cycloaddition

摘要

A highly regioselective synthesis of novel dispiroheterocycles by the cycloaddition of azomethine ylide generated through a decarboxylative route from sarcosine/proline/thiazolidine-4-carboxylic acid/1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and ninhydrin with the dipolarophile 3-arylidene-4-chromanone is described.