Reaction of Piperazine with Trimethylacetic Arylcarboxylic Anhydride; A Convenient Method for Preapring Monoacylated Pperazine Derivatives

摘要

A series of monosubstituted piperazine derivatives were obtained by the reaction of piperazine with trimethylacetic arylcarboxylic anhydrides in good yields,which were prepared in situ from arylcarboxylic acid with trimethylacetyl chloride in the presence of triethylamine.