Palladium(0)-catalyzed ring expansion reactions of hydroxy methoxyallenylisoindolinones via inter- and intramolecular carbopalladation using aryl and vinyl halides

摘要

Palladium(0)-catalyzed one-atom ring expansion of various hydroxy methoxyallenylisoindolinones 2 proceeded in the presence of aryl and vinyl halides to give the corresponding isoquinolinediones 3 in various yields. Tandem intramolecular carbo-palladation-heterocyclic ring expansion reaction of compound 5 was also achieved to give a tetracyclic compound 6. [References: 8]