Intermolecular cobalt-mediated Pauson-Khand reactions in ionic liquids

摘要

Intermolecular Pauson-Khand reactions of strained alkenes 1a-d with alkynes 2, 4, 6 and Co-2(CO)(8) were performed in [bmim]PF6 either thermally or in the presence of NMO. For comparison thermal reactions were done in toluene and NMO-promoted reactions in CH2Cl2 The results show that the ionic liquid is a suitable substitute for CH2Cl2. Yields of the NMO-promoted reaction could be improved by using a two-phase system [bmim]PF6/methylcyclohexane. [References: 41]