Design and Application of 3-Alkyl-2-vinylindoles in BrOnsted Acid Catalyzed Reactions

摘要

Our group has designed and developed 3-alkyl-2-vinylindoles as a new type of vinylindoles, which have displayed versatile reactivity in BrOnsted acid catalyzed reactions. For instance, this class of vinylindoles can act as 2C building blocks in [n+2] cyclizations, as 2,3-disubstituted indoles in dearomatizations, and as NCC building blocks in [3+2] cyclodimerizations. This article summarizes the main contributions of our group in this research field.