Highly regio- and stereoselective hydrostannylation of propargyl alcohols and ethers using dibutylchlorostannane and lithium chloride

摘要

In the presence of LiCl, dibutylehlorostannane (Bu2SnClH) reacted with gamma-unsubstituted propargyl alcohols and ethers to give gamma-stannylated allyl alcohols and ethers, respectively, with high regio- and stereoselectivity. These vinylstannane products could be successfully utilized for the Pd-catalyzed cross-coupling reaction.