Palladium-catalyzed allylic alkylation of alpha-sulfinyl carbanions under biphasic conditions

摘要

Palladium-catalyzed allylic alkylation of alpha-sulfinyl carbanions can take place under biphasic conditions. These new conditions provide a simple, mild and efficient route to allylated sulfoxides in good yields. The reaction tolerates a wide variety of EWG groups as additional carbanion stabilizing groups such as ester, acetyl, cyano, arnide, SUlfonyl and sulfinyl functions.