N-heterocyclic carbene ligands in copper-catalyzed addition of diethylzinc to N-sulfonylimines

摘要

N-Heterocyclic carbenes (NHCs) were generated in-situ from imidazolium and imidazolinium salts by deprotonation of C-2 hydrogen and were used as ligands in the copper-catalyzed addition of diethylzinc to N-sulfonylimines. The copper - NHC complexes were shown to possess an efficient ligand acceleration effect (LAE).