Introduction of bicyclic ketal chemistry: Synthesis and transformation reaction of 6,8-dioxabicyclo[3.2.1]octane skeletal system [Review]

摘要

A stereo- and regioselective bicyclic ketal synthesis and several facile one-pot transformations of bicyclic ketals are described with plausible mechanisms. Products have included delta,epsilon-unsaturated ketones, mono- and diacetoxy ketones, transketalized ketones, cis- and trans-cyclic ethers, 1,5-diketones, cis-1,2-cyclopentanediols, 2.6-disubstituted pyridines, 2,3,6-trisubstituted pyridines, and conjugated and nonconjugated cyclohexenones. [References: 130]