Highly efficient discrimination of fluorous tags by beta-cyclodextrin columns: new isolation method for fluorous mixture synthesis

摘要

High performance liquid chromatography (HPLC) packed with beta-cyclodextrin columns eluted by reversed phase or fluorous phase shows excellent discrimination of fluorous tags. beta-Cyclodextrin columns are superior to fluorous silica gel columns in view of efficient separation of compounds bearing short (CF3) to long (C9F19) tag. [References: 13]