A radical carbon-carbon bond forming reaction: Indium mediated radical addition to beta-substituted conjugated alkenes in aqueous media

摘要

Indium-mediated 1,4-addition of alkyl radical to P-substituted conjugated alkenes in aqueous media has been developed. The reaction affords 1,4-addition products to various alpha,beta-enones regiospecifically in high isolated yields. [References: 29]