Efficient synthesis of 2,3-dihydrofurans via the highly selective Pd(0)catalyzed coupling-cyclization reaction of 3,4-allenols with aryl iodides

摘要

Highly selective coupling-cyclization of 3,4-allenols with aryl iodides via the oxidative addition-exo-mode oxypalladation-reductive elimination sequence afforded 2,3-dihydrofurans efficiently. The cyclization mode and the regioselectivity observed for 3,4-allenols are unique and different from what was reported previously. [References: 41]