[Ir(cod)Cl](2)/FDPPE-catalyzed chemo- and regioselective cyclotrimerization of two different terminal alkynes to give 1,3,5-trisubstituted benzenes

摘要

[Ir(cod)Cl](2) in combination with 1,2-bis(dipentafluorophenylphosphino)ethane catalyzes chemo- and regioselective cyclotrimerization of two different alkynes. The reaction of methyl propiolate with I-hexyne gave methyl 3,5-di(n-butyl)benzoate as a single product in 88% yield.