Loss of EZH2 Does Not Enhance Oncogenic KRAS-promoted PDAC in Adult Tissue Unless Combined With Events That Affect Acinar Cell Maturation

Berger K.; Johnson C.; Lomberk G.; Howlett C.; Urrutia R.; Pin C.

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Loss of EZH2 Does Not Enhance Oncogenic KRAS-promoted PDAC in Adult Tissue Unless Combined With Events That Affect Acinar Cell Maturation

机译：除非与影响腺泡细胞成熟的事件相结合，EZH2的丧失并不能增强成年组织中致癌性KRAS促进的PDAC。

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来源
《Pancreas 》 |2016年第10期| 共1页
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Berger K.; Johnson C.; Lomberk G.; Howlett C.; Urrutia R.; Pin C.;
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正文语种 eng
中图分类消化系及腹部疾病 ;
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1. Loss of EZH2 Does Not Enhance Oncogenic KRAS-promoted PDAC in Adult Tissue Unless Combined With Events That Affect Acinar Cell Maturation [J] . Berger K., Johnson C., Lomberk G., Pancreas . 2016 ,第10期

机译：除非与影响腺泡细胞成熟的事件相结合，EZH2的丧失并不能增强成年组织中致癌性KRAS促进的PDAC。
2. hMOF (human males absent on the first), an oncogenic protein of human oral tongue squamous cell carcinoma, targeting EZH2 (enhancer of zeste homolog 2) [J] . Li Qihong, Sun Haiyan, Shu Yao, Cell Proliferation . 2015 ,第4期

机译：hMOF（人类男性第一个缺失），一种人类口腔舌鳞状细胞癌的致癌蛋白，靶向EZH2（zeste同源物2的增强子）
3. Overexpression of exogenous PAX4 combined with suppression of endogenous arx enhances beta-cell lineage specification and maturation during the ex vivo transdifferentiation of human exocrine pancreatic tissue [J] . Lima Maria J., Muir Kenneth R., Docherty Hilary M., Xenotransplantation . 2015 ,第Suppla1期

机译：外源性PAX4的过表达与内源性arx的抑制作用增强了人类外分泌胰腺组织在体外转分化过程中的β细胞谱系规格和成熟度。
4. Enhanced Cardiomyocyte Proliferation and Maturation on Fractionated Cardiac Extracellular Matrix Derived from Decellularized Native Ventricular Tissue [C] . Kyle Edmunds, Corin Williams, Ngonidzashe Madungwe, Society for Biomaterials annual meeting and exposition . 2014

机译：脱细胞天然心室组织衍生的分级心脏细胞外基质上增强的心肌细胞增殖和成熟。
5. Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC [O] . Marwa Alhothali, Mevin Mathew, Geeta Iyer, 2019

机译：芬迪林通过抑制促进肿瘤的信号传递事件来增强治疗剂对PDAC细胞的细胞毒性作用：对抗PDAC的潜在策略
6. Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC [O] . Marwa Alhothali, Mevin Mathew, Geeta Iyer, 2019

机译：丁胺通过抑制肿瘤促进信号事件，增强治疗剂对PDAC细胞的细胞毒性作用：打击PDAC的潜在策略

Loss of EZH2 Does Not Enhance Oncogenic KRAS-promoted PDAC in Adult Tissue Unless Combined With Events That Affect Acinar Cell Maturation

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