Concomitant occurrence of pulmonary invasive aspergillosis and pneumocystis pneumonia during FOLFIRINOX chemotherapy for pancreatic carcinoma

摘要

Pneumocystis jirovecii pneumonia (PCP) is widely known as an opportunistic infection in human immunodeficiency virus (HTV)-infected patients. It can also occur in patients with prolonged chemotherapy-induced neutropenia treated for hematologic malignancies and/or patients undergoing hematopoietic stem cell transplantation. This population is also at high risk of invasive aspergillosis (IA) infection. Invasive aspergillosis commonly affects patients with concomitant noninfectious lung disease, such as lung cancer, chronic obstructive bronchopulmonary disease, emphysema, bronchiectasis, pulmonary fibrosis or tuberculosis sequels.