A Concise Route to L-Azidoamino Acids: L-Azidoalanine, L-Azidohomoalanine and L-Azidonorvaline

摘要

A simple and highly efficient synthetic route to three homologous azidoamino acids, starting from inexpensive, commercially available, protected natural amino acids is reported. The products can be used to introduce bioorthogonal handles into proteins.