Prunus Armeniaca Hydroxynitrile Lyase (ParHNL) Catalyzed Asymmetric Synthesis of δ,ε-Unsaturated Cyanohydrins

摘要

Hydroxynitrile lyases (HNL) are one of the key enzymes in cyanogenic plants, catalyzing the final step in the biodegradation pathway of cyanogenic glycosides releasing HCN and the corresponding carbonyl components. We have been able to find some new plant HNL from drupe available in the northern part of the Indian subcontinent. Asymmetric cyanohydrin synthesis from y,8- unsaturated aldehydes by applying those new HNL is reported in this communication.