A Lanostane Triterpenoid and Three Cholestane Sterols from Tilia kiusiana

摘要

Kiusianins A–D (1–4) were isolated from the leaves of a Japanese endemic plant, Tilia kiusiana, together with 14 known compounds. The structures of a new lanostane-type triterpenoid 1 and three new cholestanetype sterols 2–4 were elucidated by spectroscopic methods, including two dimensional (2D) NMR. All the compounds isolated were evaluated for their cytotoxicity against two human cancer cell lines, HeLa and HL-60.