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Genomics, Epigenomics and Personalized Medicine: A Bright Future for Drug Development?

机译:基因组学,表观基因组学和个性化医学:药物开发的光明前景?

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摘要

The sequencing of the human genome marked the beginning of two new fields: personalized genomics and epigenomics. Some companies have already launched personalized genetic tests and whole genome sequencing to predict diseases. Epigenomics has also emerged in the post-genomic era with the objective of cataloguing all modifications in the DNA that have the potential to change the expression of genes. Epigenetics refers to the study of such changes and some drugs have already been launched based in epigenetic mechanisms. This is just the beginning for two fields that are in their infancy and it is clear that new medicines that could revolutionize personalized therapies are on the way.
机译:人类基因组的测序标志着两个新领域的开始:个性化基因组学和表观基因组学。一些公司已经启动了个性化的基因检测和全基因组测序来预测疾病。表观基因组学也出现在后基因组时代,其目的是对DNA中所有可能改变基因表达的修饰进行分类。表观遗传学是指对这种变化的研究,并且已经基于表观遗传学机制推出了一些药物。这仅仅是两个处于起步阶段的领域的开始,很显然,可能会革新个性化疗法的新药物正在兴起。

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