Polycyclic N-Heterocyclic Compounds. Part 591): RearrangementReactions of Fused Tricyclic 3-(2-BromoethyDpyrimidin-4(311)-ones withPrimary Amines via a Dimroth-Type Rearrangement

摘要

Reaction of some fused tricyclic 3-(2-bromoethyl)pyrimidin-4(311)-ones with primary alkyl amines gaveabnormal fused 3-alkyl-4-alkyliminopyrimidines via a Dimroth-type rearrangement, as well as normal substi-tuted 3-(2-alkylaminoethyl) derivatives in methanol. This abnormal rearrangement reaction depended on reac-tion solvent.