首页> 外文期刊>Sleep & breathing =: Schlaf & Atmung >Association of ACE I/D polymorphism with obstructive sleep apnea susceptibility: evidence based on 2,228 subjects.
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Association of ACE I/D polymorphism with obstructive sleep apnea susceptibility: evidence based on 2,228 subjects.

机译:ACE I / D多态性与阻塞性睡眠呼吸暂停易感性的关联:基于2,228名受试者的证据。

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摘要

ACE polymorphism I/D had no statistically significant association with increased OSA risk, but the II genotype of ACE may be a risk factor for OSA with hypertension in Asians. OSA cases who develop hypertension may derive from a different mechanism compared to essential hypertension. Studies with large sample size and representative population are warranted to verify this finding.
机译:ACE多态性I / D与OSA风险增加没有统计学意义的关联,但是ACE的II基因型可能是亚洲人患有OSA并发高血压的危险因素。与原发性高血压相比,发生高血压的OSA病例可能来自不同的机制。有大量样本和有代表性的研究值得证实。

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