Comparative Study of Chemical Constituents of Rhubarb from Different Origins

摘要

A comparative study of the pharmacologically active constituents of 24 rhubarb samples,which were identified genetically as Rheum tanguticum,3 intraspecies groups of R.palmatum and R.officinale,was conducted using reversed-phase high performance liquid chromatography(HPLC)methods.Thirty compounds belonging to anthraquinones,anthraquinone glucosides,dianthrones,phenylbutanones,stilbenes,flavan-3-ols,procyani-dins,galloylglucoses,acylglucoses,gallic acid,and polymeric procyanidins were analyzed quantitatively.The drug samples derived from the same botanical source showed similar chromatographic profiles,and the comparable specific shape that appeared in the 10-directed radar graphs constructed on the basis of the results of quantitative analysis indicated the relationship between chemical constituent patterns and genetic varieties of rhubarb samples.