Transformation of Cinchona Alkaloids into 1-N-Oxide Derivatives by Endophytic Xylaria sp. Isolated from Cinchona pubescens.

Shibuya H; Kitamura C; Maehara S; Nagahata M; Winarno H; Simanjuntak P; Kim HS; Wataya Y; Ohashi K

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Transformation of Cinchona Alkaloids into 1-N-Oxide Derivatives by Endophytic Xylaria sp. Isolated from Cinchona pubescens.

机译：内生木霉属植物将金鸡纳生物碱转化为1-N-氧化物衍生物。从金鸡纳pubescens分离。

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摘要

The microbial transformation of four Cinchona alkaloids (quinine, quinidine, cinchonidine, and cinchonine) by endophytic fungi isolated from Cinchona pubescens was investigated. The endophytic filamentous fungus Xylaria sp. was found to transform the Cinchona alkaloids into their 1-N-oxide derivatives.

机译：研究了从金鸡纳树分离的内生真菌对四种金鸡纳生物碱（奎宁，奎尼丁，金鸡尼定和金鸡尼碱）的微生物转化。内生丝状真菌Xylaria sp。被发现将金鸡纳生物碱转化为其1-N-氧化物衍生物。

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来源
《Chemical and Pharmaceutical Bulletin》 |2003年第1期|共4页
作者
Shibuya H; Kitamura C; Maehara S; Nagahata M; Winarno H; Simanjuntak P; Kim HS; Wataya Y; Ohashi K;
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正文语种 eng
中图分类药学;化学;
关键词
Cinchona; Transformation; NOS; Isolated; Cinchona Alkaloids; 金鸡纳树属; 金鸡纳生物碱类;

机译：Cinchona;Transformation;NOS;Isolated;Cinchona Alkaloids;金鸡纳树属;金鸡纳生物碱类;

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1. Transformation of Cinchona Alkaloids into 1-N-Oxide Derivatives by Endophytic Xylaria sp. Isolated from Cinchona pubescens. [J] . Shibuya H, Kitamura C, Maehara S, Chemical and Pharmaceutical Bulletin . 2003,第1期

机译：内生木霉属植物将金鸡纳生物碱转化为1-N-氧化物衍生物。从金鸡纳pubescens分离。
2. Bioproduction of Cinchona alkaloids by the endophytic fungus Diaporthe sp. associated with Cinchona ledgeriana [J] . Maehara S., Simanjuntak P., Kitamura C., Chemical and Pharmaceutical Bulletin . 2012,第10期

机译：内生真菌Diaporthe sp。的金鸡纳生物碱的生物生产。与Cinchona ledgeriana相关
3. Bioproduction of Cinchona Alkaloids by the Endophytic Fungus Diaporthe sp. Associated with Cinchona ledgeriana [J] . Shoji Maehara, Partomuan Simanjuntak, Chinami Kitamura, Chemical and Pharmaceutical Bulletin . 2012,第10期

机译：内生真菌Diaporthe sp。的金鸡纳生物碱的生物生产。与Cinchona ledgeriana相关
4. Culturable endophytic bacteria obtained from Cinchona ledgeriana Moens. in West Java and its antagonistic effect against Phytophthora sp. [C] . Fauzi Akhbar Anugrah, Rahmi Masita, Hanumi Oktyani Rusdi, International Conference on Life Sciences and Technology . 2020

机译：从Cinchona Ledgeriana Moens获得的培养内心细菌。在西爪哇综合症及其对植物胰酸痛的拮抗作用。
5. Synthetic and Mechanistic Studies of Cinchona Alkaloid Catalyzed Asymmetric [4+2] Addition Reactions. [D] . Bartelson, Keith J. 2012

机译：金鸡纳生物碱催化不对称[4 + 2]加成反应的合成和机理研究。
6. Phylogeny Predicts the Quantity of Antimalarial Alkaloids within the Iconic Yellow Cinchona Bark (Rubiaceae: Cinchona calisaya) [O] . Carla Maldonado, Christopher J. Barnes, Claus Cornett, -1

机译：系统发育预测标志性黄色金鸡纳树皮（茜草科：Cinchona calisaya）中抗疟疾生物碱的数量
7. Transformation of Cinchona Alkaloids into 1-N-Oxide Derivatives by Endophytic Xylaria sp. Isolated from Cinchona pubescens. [O] . Hirotaka Shibuya, Chinami Kitamura, Shoji Maehara, 2003

机译：CinChona生物碱通过内胚菌Xylaria Sp转化为1-N-氧化物衍生物。与迪尔纳群群孤立的孤立。

Transformation of Cinchona Alkaloids into 1-N-Oxide Derivatives by Endophytic Xylaria sp. Isolated from Cinchona pubescens.

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