STUDY OBJECTIVES: The aim was to assess associations between sleep duration, sleep stages, and central obesity in women. DESIGN: Cross-sectional study. SETTING: City of Uppsala, Sweden. PARTICIPANTS: Population-based sample of 400 women (range 20-70 years). INTERVENTIONS: Full-night polysomnography and measurement of anthropometric variables. MEASUREMENTS AND RESULTS: Sleep duration was inversely related to both waist circumference and sagittal abdominal diameter. Sleep duration remained inversely related to waist circumference (adj. beta = -1.22 cm/h; P = 0.016) and sagittal abdominal diameter (adj. beta = -0.46 cm/h; P = 0.001) after adjusting for potential confounders. Duration of slow wave sleep (SWS, adj. beta = -0.058 cm/min; P = 0.025) and REM sleep (adj. beta = -0.062 cm/min; P = 0.002) were both inversely related to waist circumference afteradjustments. Moreover,duration of REM sleep was inversely related to sagittal abdominal diameter (adj. beta = -0.021 cm/min; P < 0.0001). These associations were stronger in young women (age < 50 years). CONCLUSION: An inverse relationship between short sleep duration and central obesity was found in women after adjusting for confounders. Loss of SWS and REM sleep may be important factors in the association between sleep loss and central obesity.
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机译：研究目的：目的是评估妇女的睡眠时间，睡眠阶段和中枢性肥胖之间的关联。设计：横断面研究。地点：瑞典乌普萨拉市。参加者：基于人群的400名妇女样本（范围为20-70岁）。干预措施：整夜多导睡眠监测和人体测量学变量的测量。测量与结果：睡眠时间与腰围和矢状腹径成反比。调整潜在的混杂因素后，睡眠时间与腰围（调整后的beta = -1.22 cm / h; P = 0.016）和矢状腹径（调整后的beta = -0.46 cm / h; P = 0.001）呈反比关系。慢波睡眠的持续时间（SWS，调整后的beta = -0.058 cm / min; P = 0.025）和REM睡眠（调整后的beta = -0.062 cm / min; P = 0.002）与腰围调整后均呈负相关。此外，REM睡眠的持续时间与矢状腹径成反比（调节β＝ -0.021cm / min; P ＜0.0001）。这些关联在年轻女性（年龄小于50岁）中更强。结论：调整混杂因素后，女性的睡眠时间短与中枢性肥胖呈反比关系。 SWS和REM睡眠丧失可能是睡眠丧失与中枢性肥胖之间关联的重要因素。
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