Synthesis of 1-aryloxyacetyl-4-(4-nitrobenzoyl)-thiosemicarbazides under phase transfer catalysis and microwave irradiation

摘要

The 1-arloxyacetyl-4-(4-nitrobenzoyl)-thiosemicarbazides (3a-m) are synthesized via reaction of 4-nitrobenzoyl chloride with ammonium thiocyanate and aryloxyacetic acid hydrazides (2a-m) under phase transfer catalysis and microwave irradiation in excellent yield.