Enaminones in Organic Synthesis: A Novel Synthesis of 1,3,5-Trisubstituted Benzene Derivatives and of 2-Substituted-5-Aroylpyridines

摘要

Enaminones undergo self-condensation on reflux in acidic media yielding 1,3,5-trisubstituted benzene in very high yields. Reaction of enaminones 1a, b with ethyl propiolate affords 5-aroyl-1,3-benzene dicarboxylate derivatives.