Room-temperature synthesis of diindolylmethanes using silica-supported sulfuric acid as a reusable catalyst under solvent-free conditions

摘要

Efficient electrophilic substitution reactions of indoles with various aromatic and aliphatic aldehydes were carried out using a catalytic amount of H_2SO_4SiO_2 under solvent-free conditions to afford the corresponding bis(indolyl)methanes in excellent yields.