Application of wittig reaction in synthesis of novel pyridine dicarboxylic acid derivatives with high ligand activity

摘要

A series of novel conjugated molecules with two pyridine dicarboxylic acid units have been synthesized by a Wittig reaction of corresponding alkyltriphenylphosphonium salts with aromatic aldehydes. The novel pyridine dicarboxylic acid derivatives with high ligand activity were completely characterized from their mass and ~1H NMR spectra. The E-configuration of these alkenes was confirmed by infrared spectroscopic data.