A facile synthesis of pyrimidone derivatives and single-crystal characterization of pymetrozine

摘要

A facile and efficient synthetic methodology for the preparation of aza-pyrimidone and beno-pyrimidone derivatives is described, in which the triazinone ring and dihydroquinazolin-2(1H)-one was convenient constructed. The structures of all the newly synthesized compounds were characterized by mass, ~1H NMR, and infrared spectroscopy. In additional, the crystal of pymetrozine was obtained to find useful information such as configuration and molecular action mechanisms.