One-Pot Stereoselective Synthesis of (Z)-1,2-Disubstituted Vinyl Sulfones by Hydrostannylation-Stille Tandem Reaction of Acetylenic Sulfones

摘要

(Z)-1,2-Disubstituted vinyl sulfones can be stereoselectively synthesized in one pot under mild conditions, in good yields, by the palladium-catalyzed hydrostannylation of acetylenic sulfones with tributyltin hydride, followed by Stille coupling with aryl iodides.