Microwave-Assisted, One-Pot Synthesisof 5-Thia-4b,10-diaza-indeno[2,1-a]-indene-5,5-dioxide and 10H-11-Thia-5,10a-diaza-benzo[b]fluorene-11,11-dioxide

摘要

The one-pot, microwave-assisted synthesis of 5-thia-4b,10-diaza-indeno[2,1-a]indene-5,5-d ioxide (6) and 10H-1 1 -thia-5, I Oa-diaza-benzo[b]fluorene-11,11 -dioxide (7) from 1,2-phenylenediamine and 2-aminobenzyla-mine, respectively, is described. Generation of a sulfonamide through reactionof the appropriate diamine with 2-cyanobenzenesulfonyl chloride is followedby a multistep intramolecular transformation and subsequent elimination ofammonia to provide the corresponding tetracycle in good yield.