Synthesis of new functionalized chiral ionic liquid and its organocatalytic asymmetric michael addition

摘要

A novel recyclable functionalized chiral ionic liquid has been developed to promote asymmetric Michael additions of cyclohexanone to both aryl and alkyl nitroolefins in the presence of 20mol% of organocatalyst 4 in MeOH. The process affords synthetically valuable chiral products in good yields (up to 93%) and high enantioselectivities (up to 92%). The chiral ionic liquid could be easily reused six times without remarkable decrease in yields and enantioselectivities.