H_6P_2W_(18)O_(62)-18H_2O, a green and reusable catalyst for the three-component, one-pot synthesis of 4,6-diarylpyrimidin-2(1H)-ones under solvent-free conditions

摘要

Three-component, one-pot synthesis of 4,6-diarylpyrimidin-2(1H)-ones and 9-phenyl-8-oxa-10,12-diaza-tricyclo[7.3.1.0~(2,7)]trideca-2(7),3,5- trien-11-one by condensing acetophenone derivatives, aldehydes, and urea in the presence of trimethylsilyl chloride using a catalytic amount of H _6P_2W_(18)O_(62)-18H_2O under solvent-free conditions is reported.