A NOVEL SYNTHETIC ROUTE TO DIHYDRO- AND ALPHA-HYDROXYTETRAHYDRO-FURAN DERIVATIVES

摘要

1-(3-Morpholinoprop-2-enyl)benzotriazole (1) provides a three carbon unit for the construction of dihydro- and tetrahydro-furan rings by one pot procedures. Lithiation of 1 followed by reaction with diaryl ketones Save 2,5-dihydro- and/or alpha-hydroxytetrahydro-furans, whereas successive reactions with iodoalkanes and diaryl ketones yielded 2,3-dihydrofurans. [References: 27]