Regioselective Aromatic Electrophilic Bromination with Dioxane Dibromide Under Solvent-Free Conditions

摘要

Highly regioselective ring bromination of aromatic compounds has been accomplished with high yields and good purity using dioxane dibromide (DD) under solvent-free conditions.Notable features of this methodology include operational simplicity,rapid reactions,excellent control over the degree of bromination,and tolerance of various functional groups during the reaction.