Ytterbium(III) triflate-catalyzed stereoselective synthesis of beta-lactams via [2+2] cyclocondensation in ionic liquid

摘要

Catalyzed by ytterbium(III) triflate [Yb(OTf)(3)], beta-lactams were stereoselectively synthesized from imines and acetyl chlorides in ionic liquid under mild conditions. The ionic liquid and catalyst could be recycled and reused as opposed to traditional solvent - catalyst systems.