Carbon-Carbon Bond Formation by Radical Cyclization: Regioselective Synthesis of Spiro Heterocyclic Compounds by ~nBu_3SnH-Mediated Reaction

摘要

Several spiro heterocyclic compounds have been regioselectively synthesized in excellent yield by ~nBu_3SnH-AIBN-mediated radical cyclization of 4-(2'-bromoaryloxymethyl)-l-methylquinolin-2(lH)-ones in refluxing benzene under nitrogen for 4 h.