New triterpenoid saponins from fruits specimens of panax japonicus collected in Kumamoto and Miyazaki Prefectures (1)

摘要

Seven new dammarane-type triterpenoid saponins, chikusetsusaponin FK _1 (1), chikusetsusaponin FK _2(2), chikusetsusaponin FK _3 (3), chikusetsusaponin FK _4 (4), chikusetsusaponin FK _5 (5), chikusetsusaponin FK _6(6), and chikusetsusaponin FK_7 (7), and eleven known triterpenoid saponins, ginsenoside Rb _3 (9), ginsenoside Rc (10), chikusetsusaponin VI (11), ginsenoside Re (12), ginsenoside Rg _1 (13), pseudo-ginsenoside RS _1 (14), notoginsenoside R1 (15), chikusetsusaponin L _5 (17), chikusetsusaponin L _(10) (18), chikusetsusaponin IVa (19), and chikusetsusaponin V (20), were isolated from the fruits of Panax japonicus C. A. MEYER, collected in Kumamoto prefecture, Japan, and two new dammarane-type triterpenoid saponin, chikusetsusaponin FK _5(5) and chikusetsusaponin FM1 (8), and five known triterpenoid saponins, ginsenoside Rb _3 (9), ginsenoside Rc (10), ginsenoside Re (12), ginsenoside Rg _1 (13), and floralquinquenoside E (16), were isolated from the fruits of P. japonicus C. A. MEYER, collected in Miyazaki prefecture, Japan. The structures of new chikusetsusaponins were elucidated on the basis of chemical and physicochemical evidences.