Controlled antibiotic-releasing Antheraea assama silk fibroin suture for infection prevention and fast wound healing

摘要

Background. The quest for developing silk fibroin as a biomaterial for drug release systems continues to draw research interest owing to its impressive mechanical properties as well as biocompatibility and biodegradability. The aim of this study is to develop low-temperature O-2 plasma-treated muga (Antheraea assama) silk fibroin (AASF) yarn impregnated with amoxicillin trihydrate as controlled antibiotic-releasing suture (AASF/O-2/AMOX) for preventing postoperative site bacterial infection and fast wound healing