Allylstannanes and vinylstannanes from stannylcupration of C-C multiple bonds.Recent advances and applications in organic synthesis

摘要

The stannylcupration of allenes and alkynes has emerged as a powerful tool for the synthesis of allyl- and vinylorganostannanes.The regio- and stereoselectivity of this reaction depends upon the nature of the cuprate,the temperature and the structure of the allene or alkyne.The versatility and synthetic scope of the tin-synthons thus obtained is very wide.These intermediates have been employed as precursors in the key step of the stereoselective synthesis of many natural products,heterocycles or conjugated polyenes.This tutorial review shows a general survey of the recent advances in this area together with the contribution of our lab to this field.