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Seasonal variation and atypical presentation of idiopathic intracranial hypertension in pre-pubertal children.

机译:青春期前儿童特发性颅内高压的季节性变化和非典型表现。

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摘要

Idiopathic intracranial hypertension is an enigmatic disorder of elevated cerebrospinal fluid pressure. In adulthood, patients are typically obese women of childbearing age; however, in young children the clinical picture is strikingly different, indicating age-related differences in the aetiology of idiopathic intracranial hypertension. To investigate this phenomenon, we analysed the clinical details of 15 pre-pubertal children with the diagnosis of idiopathic intracranial hypertension. Evaluating the date of initial presentation, we discovered a distinct seasonal variation. Ten patients presented between November and March, thus coinciding with the typical season of paediatric viral and bacterial infections in Germany. Therefore, we suggest an association between intracranial hypertension and possibly concurrent infections in these children. Moreover, eight children presented only with ophthalmologic findings without any other obvious symptoms, raising questions regarding the incidence of undetected cases, particularly in this age group.
机译:特发性颅内高压是一种脑脊髓液压力升高的神秘疾病。在成年期,患者通常是育龄的肥胖妇女。然而,在幼儿中,临床表现却截然不同,表明与年龄有关的特发性颅内高压的病因学差异。为了调查这种现象,我们分析了15例青春期前儿童的诊断为特发性颅内高压的临床细节。在评估首次展示的日期时,我们发现了明显的季节性变化。 11月至3月之间出现了10例患者,因此与德国典型的小儿病毒和细菌感染季节相吻合。因此,我们建议这些儿童的颅内高压与可能的并发感染之间存在关联。此外,八名儿童仅表现出眼科检查结果,而没有任何其他明显症状,这引发了关于未发现病例的发生率的疑问,尤其是在这个年龄组中。

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