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Diabetes and early postoperative outcomes following lumbar fusion.

机译:糖尿病和腰椎融合术后早期结果。

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STUDY DESIGN: Retrospective cohort study using data from the Nationwide Inpatient Sample administrative data from 1988 through 2003. OBJECTIVE: To examine perioperative morbidity and mortality for patients with and without diabetes mellitus following lumbar spinal fusion. SUMMARY OF BACKGROUND DATA: Diabetes has been associated with worse outcomes in a variety of orthopedic procedures including spinal surgery. There is limited evidence that diabetic patients have more complications following lumbar fusion with little published data to support this conclusion. METHODS: Data from 197,461 patients who underwent lumbar fusion were included. Over 11,000 patients (5.6%) with a postoperative diagnosis of diabetes mellitus were identified. Selected variables were used for comparison of patients with and without diabetes. Bivariate statistical analyses compared postoperative complication rates while multivariate statistics were used to determine likelihood of complications with diabetes. RESULTS: Bivariate analysis demonstrated that diabetes was significantly associated with postoperative infection, need for transfusion, pneumonia, in-hospital mortality, and nonroutine discharge (P
机译:研究设计:回顾性队列研究,使用了1988年至2003年全国住院患者样本管理数据。目的:研究腰椎融合术后有无糖尿病患者的围手术期发病率和死亡率。背景数据摘要:在包括脊柱外科手术在内的各种骨科手术中,糖尿病与不良结局相关。仅有有限的证据表明,糖尿病患者腰椎融合术后发生的并发症更多,几乎没有公开的数据支持该结论。方法:纳入197,461例接受腰椎融合术的患者的数据。识别出超过11,000名术后诊断为糖尿病的患者(5.6%)。选择的变量用于比较有无糖尿病的患者。二元统计分析比较了术后并发症发生率,而多元统计被用于确定糖尿病并发症的可能性。结果:双因素分析表明,糖尿病与术后感染,需要输血,肺炎,院内死亡率和非常规出院显着相关(P <或= 0.001)。调整后的多元回归分析表明,尽管感染,输血和非常规排尿仍然非常显着(P <或= 0.002),但死亡率无差异。糖尿病患者的通货膨胀调整后总费用也显着增加,并且住院时间增加(P <0.001)。结论:这项对美国住院患者的全国代表性研究提供了证据,表明糖尿病与术后并发症,非常规出院,总住院费用增加以及腰椎融合术后住院时间增加的风险有关。确定因果关系以及糖尿病控制对这些变量的潜在影响的前瞻性研究尚未完成。

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