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Recent Diabetes Issues Affecting the Primary Care Clinician

机译:影响初级保健医生的近期糖尿病问题

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摘要

Diabetes accounts for millions of office visits each year to primary care offices in the United States. Successful care of the patient with type 2 diabetes requires not only focus on glucose management but also on comorbidities such as hypertension, dys-lipidemia and obesity which are closely linked to microvascular and macrovascular complications. Primary care clinicians must stay abreast of frequently published diabetes literature and new treatments to care for these increasingly complex patients. Metformin and its effect on B12 absorption continues to be an issue encountered by clinicians in daily clinical practice. There has also been recent discussion regarding the increased risk of diabetes with statins; data to date on this issue have been conflicting. Rosiglitazone continues to face public scrutiny and there are now Food and Drug Administration regulations regarding its increased risk of cardiovascular disease. Liraglutide and saxagliptin represent new treatment options for type 2 diabetes, increasing the available options for treating this complex disease. A review of the primary literature involving these topics is provided.
机译:糖尿病每年占美国基层医疗机构数百万的办公室就诊次数。对2型糖尿病患者的成功护理不仅需要关注血糖管理,而且还需要与微血管和大血管并发症密切相关的合并症,例如高血压,血脂异常和肥胖症。初级保健临床医生必须与经常出版的糖尿病文献和新疗法保持同步,以照顾这些日益复杂的患者。二甲双胍及其对B12吸收的影响仍然是临床医生在日常临床实践中遇到的问题。他汀类药物会增加患糖尿病的风险。迄今为止,有关此问题的数据存在冲突。罗格列酮继续受到公众的审查,目前美国食品药品监督管理局(FDA)已制定有关其增加心血管疾病风险的法规。利拉鲁肽和沙格列汀代表2型糖尿病的新治疗选择,从而增加了治疗这种复杂疾病的可用选择。提供了涉及这些主题的主要文献的综述。

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